Maurizio Grimaldi,Judith Varady Hobrath,Subramaniam Ananthan,Joseph A. Maddry
申请号：
US14797773
公开号：
US20160022691A1
申请日:
2015.07.13
申请国别(地区):
US
年份:
2016
代理人:
摘要：
Methods for enhancing memory and/or learning and prevent neurodegeneration by administration of certain heterocyclic and aromatic compounds are described. The methods are particularly useful for treating patients suffering from a neurodegenerative disease such as (without limitation) Alzheimers, Parkinsonss, and Lou Gehrigs (ALS) disease or memory or learning impairment. A neuronal human cell-based assay that assess NF-kB gene up-regulation using a luciferase reporter is also provided that screens for compounds useful in methods for enhancing memory or learning.
