Maurizio Grimaldi,Judith Varady Hobrath,Subramaniam Ananthan,Joseph A. Maddry
申请号：
US16504431
公开号：
US20200171040A1
申请日:
2019.07.08
申请国别(地区):
US
年份:
2020
代理人:
摘要：
Methods for enhancing memory and/or learning and prevent neurodegeneration by administration of certain heterocyclic and aromatic compounds are described. The methods are particularly useful for treating patients suffering from a neurodegenerative disease such as (without limitation) Alzheimer's, Parkinsons's, Lou Gehrig's (ALS) disease or memory or learning impairment. A neuronal human cell-based assay that assess NF-kB gene up-regulation using a luciferase reporter is also provided that screens for compounds useful in methods for enhancing memory or learning.
