Maurizio Grimaldi,Judith Varady Hobrath,Subramaniam Ananthan,Joseph A. Maddry
申请号:
US13501934
公开号:
US09095596B2
申请日:
2010.10.14
申请国别(地区):
US
年份:
2015
代理人:
摘要:
Methods for enhancing memory and/or learning and prevent neurodegeneration by administration of certain heterocyclic and aromatic compounds are described. The methods are particularly useful for treating patients suffering from a neurodegenerative disease such as (without limitation) Alzheimers, Parkinsonss, Lou Gehrigs (ALS) disease or memory or learning impairment. A neuronal human cell-based assay that assess NF-kB gene up-regulation using a luciferase reporter is also provided that screens for compounds useful in methods for enhancing memory or learning.