Die Erfindung betrifft 2-(R2-Thio)-10-[3-(4-R1-piperazin-1-yl)propyl]-10H-phenothiazine gemäß der allgemeinen Formel Izur Behandlung neurodegenerativer Erkrankungen.The invention relates to 2- (R2-thio) -10- [3- (4-R1-piperazin-1-yl) propyl] -10H-phenothiazines according to the general formula I for the treatment of neurodegenerative diseases.