PROCESS FOR PRODUCING SUGAR CHAIN DERIVATIVE, STRUCTURE ANALYSIS METHOD, AND SUGAR CHAIN DERIVATIVE

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专利权人:

OTSUKA CHEM CO LTD

发明人:

申请号：

JP20120077958

公开号：

JP2012162542(A)

申请日:

2012.03.29

申请国别(地区):

日本

年份:

2012

代理人:

摘要：

PROBLEM TO BE SOLVED: To provide a process for preparing an oligosaccharide derivative from an oligosaccharide mixture. SOLUTION: The process for preparing the oligosaccharide derivative includes the steps of: (a) introducing a lipophilic group into oligosaccharides of the mixture to obtain a mixture of oligosaccharide derivatives; (b) treating the oligosaccharide derivative mixture by serotonin affinity column chromatography; (c) conducting normal phase chromatography with use of an amino column or amide column after the step (b); and (d) treating the resulting eluate with a glycosidase before the step (c). COPYRIGHT: (C)2012,JPO&INPIT

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