The present invention refers to pharmaceutical formulations obtained from the aqueous extract of the fungus Agaricus blazei and its purified fractions for the treatment of leishmaniasis. More particularly, the present invention discloses formulations preferably for topic and oral use, in form of solid, semi-solid and liquid pharmaceutical formulations selected from a group consisting of gel, cream, ointment, pastes, emulsions in general, solutions, tablets and capsules for the treatment of canine and human cutaneous and visceral leishmaniasis.
