The present invention is directed to bicyclic spiropiperidine compounds of formula (I) which are inhibitors of the beta-secretase enzyme and that are useful in the treatment of diseases in which the beta-secretase enzyme is involved, such as Alzheimers disease. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the treatment of such diseases in which the beta-secretase enzyme is involved.La présente invention concerne des composés de spiropipéridine bi-cyclique de formule (I) qui sont des inhibiteurs de lenzyme bêta-sécrétase et qui sont utiles pour le traitement de maladies dans lesquelles lenzyme de bêta-sécrétase est impliquée, comme la maladie dAlzheimer. Linvention concerne également des compositions pharmaceutiques comprenant ces composés et lutilisation de ces composés et compositions pour le traitement de maladies dans lesquelles lenzyme de bêta-sécrétase est impliquée.
