The present invention is directed to spiropiperidine compounds of formula (I) which are inhibitors of the beta-secretase enzyme and that are useful in the treatment of diseases in which the beta-secretase enzyme is involved, such as Alzheimers disease. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the treatment of such diseases in which the beta-secretase enzyme is involved.Composés de spiropipéridine de formule (I), représentant des inhibiteurs de lenzyme bêta-sécrétase et utilisés dans le traitement de maladies dans lesquelles lenzyme bêta-sécrétase est appliquée, notamment la maladie dAlzheimer. Compositions pharmaceutiques comprenant ces composés, lutilisation et des compositions de des composés dans le traitement de maladies impliquant lenzyme bêta-sécrétase.
