The specimen material is made to contact the cell which reveals the Kv3.2 protein, cation inflow to inside the same cell, when making the specimen material contact, process is included by comparing with the cation inflow to inside the aforementioned cell, saltiness reception is substituted, saltiness adjustment material such as the chemical compound which you reinforce or inhibit, or the screening is done.Kv3.2タンパク質を発現する細胞に被検物質を接触させ、同細胞内への陽イオン流入を、被検物質を接触させないときの前記細胞内への陽イオン流入と比較することにより、工程を含む、塩味受容を代替、増強または阻害する化合物等の、塩味調節物質をスクリーニングする。