The Board of Regents of the University of Texas System
发明人:
Olson, Eric N.,Bi, Pengpeng
申请号:
AU2018225436
公开号:
AU2018225436A1
申请日:
2018.02.14
申请国别(地区):
AU
年份:
2019
代理人:
摘要:
The present disclosure describes the fusogenic promiting activity of the Myomixer protein. This polypeptide, when expressed in non-muscle cells with the Myomaker protein, is able to increase fusion of the cell with a muscle cell, but not with other non-muscle cells, as compared to cells only expression the Myomaker protein. The use of this protein and cells expressing it in the delivery of exogenous genetic material to muscle cells also is described.