The Board of Regents of the University of Texas System
发明人:
Eric N. OLSON,Pengpeng BI
申请号:
US16487937
公开号:
US20190382732A1
申请日:
2018.02.14
申请国别(地区):
US
年份:
2019
代理人:
摘要:
The present disclosure describes the fusogenic promoting activity of the Myomixer protein. This polypeptide, when expressed in non-muscle cells with the Myomaker protein, is able to increase fusion of the cell with a muscle cell, but not with other non-muscle cells, as compared to cells only expression the Myomaker protein. The use of this protein and cells expressing it in the delivery of exogenous genetic material to muscle cells also is described.