ALEKSANDR KOLESNIKOV,HUIYONG HU,STEVEN DO,VICKIE H. TSUI,XIAOJING WANG
申请号:
BR112014029674
公开号:
BR112014029674A2
申请日:
2013.06.26
申请国别(地区):
BR
年份:
2017
代理人:
摘要:
5-Azaindazole compounds of Formula I, including stereoisomers, geometric isomers, tautomers, and pharmaceutically acceptable salts thereof, are useful for inhibiting Pim kinase, and for treating disorders such as cancer mediated by Pim kinase. Methods of using compounds of Formula I for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed.