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COMPOSITION FOR STABILIZATION OF PROTEINS WHICH DOES NOT CONTAIN EXCIPIENTS FROM MAMMALS
专利权人:
МЕРЦ ФАРМА ГМБХ унд КО. КГАА (DE)
发明人:
ТЭЙЛОР Харольд (DE),БУРГЕР Маркус (DE),МАНДЕР Герд Й. (DE)
申请号:
RU2011146541/15
公开号:
RU2011146541A
申请日:
2010.04.16
申请国别(地区):
RU
年份:
2013
代理人:
摘要:
1. A composition containing: (a) a hydrophilic polymer, (b) a mixture of polyalcohol and sugar, where the mass ratio of polyalcohol to sugar is from 2: 1 to 5: 1 (wt.%), (C) detergent, and even the specified composition contains stabilizing proteins. 2. The composition according to claim 1, where the hydrophilic polymer is selected from the group consisting of hyaluronic acid, polyvinylpyrrolidone (PVP), copolymers of N-vinylpyrrolidone, a cellulose derivative, wherein said cellulose derivative is selected from the group consisting of hydroxypropyl methylcellulose, hydroxypropyl cellulose, hydroxyethyl cellulose, hydroxyethyl cellulose, hydroxyethyl cellulose, hydroxyethyl cellulose, hydroxyethyl cellulose, hydroxyethyl cellulose, hydroxyethyl cellulose, hydroxyethyl cellulose, hydroxyethyl cellulose, hydroxyethyl cellulose, hydroxyethyl cellulose, hydroxyethyl cellulose, hydroxyethyl cellulose, hydroxyethyl cellulose, hydroxyethyl cellulose, hydroxyethyl cellulose, hydroxyethyl cellulose, hydroxyethyl cellulose, hydroxyethyl cellulose , dextran, polyethylene glycol (PEG), block copolymers of PEG / PPG, homo- and copolymers of acrylic and methacrylic acid, polyurethanes, polyvinyl alcohol, polyvinyl ethers, opolimerov based on maleic anhydride, polyesters, vinyl amines, polyethylene imines, polyethylene oxides, poly (carboxylic acids), polyamides, polyanhydrides, and polyphosphazenes smesey.3. The composition according to claim 1, where the polyalcohol is selected from the group consisting of mannitol, inositol, lactylol, isomalt, xylitol, erythritol, sorbitol, and mixtures thereof. The composition according to claim 2, where the polyalcohol is selected from the group consisting of mannitol, inositol, lactylol, isomalt, xylitol, erythritol, sorbitol, and mixtures thereof. The composition according to any one of claims 1 to 4, wherein the sugar is selected from the group consisting of monosaccharides, disaccharides, polysaccharides and mixtures thereof. 6. A composit
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