MITCHELL, SCOTT A.,CURRIE, KEVIN S.,BLOMGREN, PETER A.,KROPF, JEFFREY E.,LEE, SEUNG H.,XU, JIANJUN,STAFFORD, DOUGLAS G.,BARBOSA, ANTONIO J., JR.,ZHAO, ZHONGDONG,HARDING, JAMES P.,ARMISTEAD, DAVID M.
申请号:
CA2746023
公开号:
CA2746023C
申请日:
2009.12.07
申请国别(地区):
CA
年份:
2018
代理人:
摘要:
Certain imidazopyrazines of Formula (I): wherein R1 , R2, R3, R4 and R5 aredescribedherein and pharmaceutical compositions thereof are provided herein(see formula I)The compounds may be used as Syk imhibitors. Also provided are methods fordetermining the presence or absence of Syk kinase in a sample.