TONKS, NICHOLAS,KRISHNAN, NAVASONA,GRILL, ANDREAS,SARD, HOWARD
申请号:
CA3081815
公开号:
CA3081815A1
申请日:
2018.11.06
申请国别(地区):
CA
年份:
2019
代理人:
摘要:
Provided is a method of forming a copper-containing complex, including contacting a sample containing copper with a compound of Formula (I): wherein R is -OH or -O-CH3. Also provided is a method of inhibiting enzymatic activity of a kinase in a sample, including contacting the sample with a compound of Formula (I). Further provided is a method of administering to a subject a pharmaceutical composition including a compound of Formula (I) optionally complexed with copper. Also provided is a pharmaceutical composition including copper complexed with a compound of Formula (I).