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Antigen-binding molecule for promoting disappearance of antigen via FcyRIIB
专利权人:
Chugai Seiyaku Kabushiki Kaisha
发明人:
IGAWA, Tomoyuki,MAEDA, Atsuhiko,IWAYANAGI, Yuki,HARAYA, Kenta,KATADA, Hitoshi,KADONO, Shojiro,MIMOTO, Futa
申请号:
AU2018202643
公开号:
AU2018202643A1
申请日:
2018.04.16
申请国别(地区):
AU
年份:
2018
代理人:
摘要:
#$%^&*AU2018202643A120180510.pdf#####ABSTRACT The present invention provides antigen-binding molecules containing (i) an antigen binding domain whose antigen-binding activity varies depending on ion concentration conditions, (ii) an Fcy-binding domain having Fey RIlb-selective binding activity, 5 and (iii) an FcRn-binding domain having FcRn-binding activity under an acidic pH range condition, and methods of decreasing plasma antigen concentration as compared to before administering the molecule, which include the step of administering the molecule.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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