JAE HYUN PARK,JONG SOO WOO,YONG IL KIM,YOUNG JUN NA,MIN JUNG KIM,YOUNG-HUN KIM
申请号：
PT11780838
公开号：
PT2568972T
申请日:
2011.05.13
申请国别(地区):
PT
年份:
2017
代理人:
摘要：
Provided is a pharmaceutical formulation in the form of a bilayered tablet consisting of a first layer containing irbesartan or a pharmaceutically acceptable salt thereof and a second layer containing an HMG-CoA reductase inhibitor and a basic additive, which can improve the dissolution rate and stability of irbesartan and an HMG-CoA reductase inhibitor to enhance the bioavailability of the drug compared to conventional complex formulations and to minimize the generation of the related compounds, thereby being effectively used as a stable and superior therapeutic agent for hypertension and hypercholesterolemia.
