Lancaster, Thomas M.,Zion, Todd C.,Sathiyaseelan, Thillainayagam,Thillainayagam, Sylaja
申请号:
AU2020227002
公开号:
AU2020227002A1
申请日:
2020.08.31
申请国别(地区):
AU
年份:
2020
代理人:
摘要:
#$%^&*AU2020227002A120200917.pdf#####Abstract The present disclosure relates generally to compositions of insulin-Fc (e.g., proinsulin-Fc) fusion proteins and their use to treat autoimmune disease, e.g., autoimmune diabetes, e.g., Type 1 diabetes.WO 2018/107117 PCT/US2017/065456 1/20 FIGURE 1A B-Chain A-Chain (N-terminus) Linker C-peptide Fc Fragment FIGURE lB VNINO AMC