#$%^&*AU2018201965B220191121.pdf#####: amt Interwoven NRPortbl DCC AMT 16669396_l.docx-20/03/2018 ABSTRACT A method of treating, preventing, or delaying the progression of Type 1 diabetes mellitus autoimmunity by administering an effective amount of a cytotoxic T-lymphocyteassociated antigen 4 (CTLA4) molecule is provided herewith. The CTLA4 molecule may be a fusion protein of a CTLA4 extracellular region and an immunoglobulin, such as abatacept.