1,4-OXAZEPINES EN TANT QU'INHIBITEURS DE BACE1 ET/OU BACE2

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专利权人:

SIENA BIOTECH S.P.A;F. HOFFMANN-LA ROCHE AG

发明人:

HILPERT, HANS,NARQUIZIAN, ROBERT

申请号：

CA2822534

公开号：

CA2822534A1

申请日:

2012.02.13

申请国别(地区):

CA

年份:

2012

代理人:

摘要：

This invention relates to compounds of the formula wherein and R1 to R3 are as described below, or to pharmaceutically acceptable salts thereof. These compounds are BACE1 and/or BACE2 inhibitors and can be used as medicaments for the therapeutic and/or prophylactic treatment of diseases such as Alzheimer's disease, diabetes, particularly type 2 diabetes, and other metabolic disorders.

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中国工程科技知识中心

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http://www.ckcest.cn/home/