NARQUIZIAN, ROBERT,PINARD, EMMANUEL,WOSTL, WOLFGANG
申请号：
CA2833813
公开号：
CA2833813A1
申请日:
2012.05.24
申请国别(地区):
CA
年份:
2012
代理人:
摘要：
The present invention provides spiro-[l,3]-oxazines and spiro-[l,4]-oxazepines of formula (I) having BACE1 and/or BACE2 inhibitory activity, their manufacture, pharmaceutical compositions containing them and their use as therapeutically active substances. The active compounds of the present invention are useful in the therapeutic and/or prophylactic treatment of e.g. Alzheimer's disease and type 2 diabetes.
