DERIVES D'AMIDE 5-(HETERO)ARYLPYRAZOL-3-CARBOXYLIQUE OU D'AMIDE 1-(HETERO)ARYLTRIAZOL-4-CARBOXYLIQUE UTILES POUR LE TRAITEMENT, ENTRE AUTRES, DE LA FIBROSE KYSTIQUE

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专利权人:

INC.;PROTEOSTASIS THERAPEUTICS

发明人:

BASTOS, CECILIA M.,MUNOZ, BENITO,TAIT, BRADLEY

申请号：

CA2971855

公开号：

CA2971855A1

申请日:

2015.12.23

申请国别(地区):

CA

年份:

2016

代理人:

摘要：

The present disclosure is based, in part, on the discovery that disclosed compounds such as those having Formula (IVa), (Va), (IV), or (V) can increase cystic fibrosis transmembrane conductance regulator (CFTR) activity as measured in human bronchial epithelial (hBE) cells.

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中国工程科技知识中心

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http://www.ckcest.cn/home/