Machine tool for the production of profiles, such as gearing systems on a workpiece, by means of a rotoncally driven machining tool by generating grinding, profile grinding, generating milling and/or profile milling, having at least one workpiece receiving device, a workpiece machining device and an optional machining tool profiling device. According to the invention, the workpiece machining device is borne by a machine base that has a tangential carriage, a radial carriage, a lifting carriage and a rotational carriage. With this specific construction, the workpiece machining device is guided moveably in all spatial directions with respect to the workpiece receiving device and also, if available, with respect to the machining tool profiling device.