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USE OF INHIBITORS OF BRUTON'S TYROSINE KINASE (BTK)
专利权人:
Pharmacyclics; Inc.
发明人:
Joseph J. BUGGY,Laurence Elias,Gwen Fyfe,Eric Hedrick,David J. Loury,Tarak D. Mody
申请号:
US14188390
公开号:
US20150031710A1
申请日:
2014.02.24
申请国别(地区):
US
年份:
2015
代理人:
摘要:
Disclosed herein are methods for treating a cancer comprising: a. administering a Btk inhibitor to a subject sufficient to result in an increase or appearance in the blood of a subpopulation of lymphocytes defined by immunophenotyping; b. determining the expression profile of one or more biomarkers from one or more subpopulation of lymphocytes; and c. administering a second agent based on the determined expression profile.
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