Joseph J. Buggy;Eric Hedrick;Gwen Fyfe;Tarak D. Mody;David J. Loury;Laurence Elias
发明人:
Joseph J. Buggy,Laurence Elias,Gwen Fyfe,Eric Hedrick,David J. Loury,Tarak D. Mody
申请号:
US13869700
公开号:
US20130310402A1
申请日:
2013.04.24
申请国别(地区):
US
年份:
2013
代理人:
摘要:
Disclosed herein are methods for treating a cancer comprising: a. administering a Btk inhibitor to a subject sufficient to result in an increase or appearance in the blood of a subpopulation of lymphocytes defined by immunophenotyping; b. determining the expression profile of one or more biomarkers from one or more subpopulation of lymphocytes; and c. administering a second agent based on the determined expression profile.