Joseph J. Buggy,Gwen Fyfe,Lee Honigberg,David J. Loury
申请号:
US16536058
公开号:
US20190358234A1
申请日:
2019.08.08
申请国别(地区):
US
年份:
2019
代理人:
摘要:
Disclosed herein are methods for treating a cancer comprising: a. administering a Btk inhibitor to a subject sufficient to result in an increase or appearance in the blood of a subpopulation of lymphocytes defined by immunophenotyping; b. determining the expression profile of one or more biomarkers from one or more subpopulation of lymphocytes; and c. administering a second agent based on the determined expression profile.