And to provide a method in which propagating kidney somatic stem cells efficiently. The following steps (A) and (B) including a method for manufacturing a kidney somatic stem cells: (A) in a cell population comprising cells that make up the kidney, S phase is passed through the G0 phase or G1 phase step expressing the gene of a protein having the activity to transition to and (B) step of the cells obtained in step (a) are cultured in the presence of extracellular growth factors.腎臓由来体性幹細胞を効率的に増殖する方法等を提供することを課題とする。以下の工程(A)及び(B)を含む、腎臓由来体性幹細胞の製造方法:(A)腎臓を構成する細胞を含む細胞群において、G0期又はG1期を通過させS期へと移行させる活性を有するタンパク質の遺伝子を発現させる工程;及び(B)工程(A)で得られた細胞を細胞外増殖因子の存在下で培養する工程。
