The invention relates to a method and to a device for filling a medical packaging formed as a pouch. Preferably, the packaging is filled with liquid via a port, wherein the port is aerated with a protective gas, such as nitrogen, for example, during filling According to the invention, prior to filling with liquid, the packaging is filled with an inert gas, such as nitrogen, for example, which then provides the headspace of the filled and closed pouch. This results in a particularly low oxygen content in the headspace of the pouch.
