The syringe includes a hollow body with at least one free-floating piston and a plunger within the body, with the piston between the plunger and a proximal end of the body. A manifold is provided lateral to the body. The manifold leads to an input/output tip. The manifold includes a front port located between the piston and the proximal end of the body and a rear port spaced from the proximal end of the body. The manifold includes at least one flow path leading from the input/output tip to at least one of the front port and/or the rear port. A first fluid fills a rear chamber distal to the piston and then the manifold is adjusted to fill second fluid into a front chamber proximal of the piston, and then the manifold is adjusted to allow sequential delivery of the second fluid and the first fluid.
