Cycloalkyl derivatives pirrolo [2,3-d] pyrimidine amino - 4 - il useful as inhibitors of Janus Kinases and related Pharmaceutical compositions containing such compounds
Brown, Matthew Frank,Fenwick, Ashley Edward,Flanagan, Mark Edward,Gonzales, Andrea,Johnson, Timothy Allan,Kaila, Neelu,Mitton-Fry, Mark J.,Parikh, Mihir D.,Strohbach, Joseph Walter,Tenbrink, Ruth E.,T
申请号：
CU20150078
公开号：
CU24275B1
申请日:
2014.02.11
申请国别(地区):
CU
年份:
2017
代理人:
摘要：
In this document, the derivative of pyrethroid [2-3-d] pyridine-4-il amine is an effective quinas Janus inhibitor, especially Jak1, as well as the treatment of arthritis, autoimmune diseases, cancer, diabetes, eye diseases, intestinal inflammation, neurodegenerative diseases, chronic diseases and other diseases. Skin, allergic reactions, asthma and rejection of transplantation. Formula: space of lt； / P gt； P gt； frmula lt； / P gt；<；p>；En la presente, se describen derivados de pirrolo [2-3-d] pirimidina-4-il amino útiles como inhibidores de quinasas Janus y en particular la JAK1 y tratamiento de condiciones tales como artritis, enfermedades autoinmunes, cáncer, diabetes, enfermedades de los ojos, inflamacion intestinal, enfermedades neurodegenarativas, enfermedades de la piel, reacciones alérgicas, asma y rechazos de trasplantes. De fórmula:<；/p>； <；p>；ESPACIO PARA FÓRMULA<；/p>；
