TIANJIN TASLY PHARMACEUTICAL CO., LTD., CHINA;TASLY PHARMACEUTICAL GROUP CO., LTD.
发明人:
YAN, XIJUN,WU, NAIFENG,GUO, ZHIXIN,YE, ZHENGLIANG,LIU, YAN
申请号：
ES03017260
公开号：
ES2469490T3
申请日:
2003.07.30
申请国别(地区):
ES
年份:
2014
代理人:
摘要：
A process for the preparation of a composition for the treatment of chronic stable angina pectoris, characterized in that it comprises the steps of: (a) obtaining a crushed starting material as follows: 80.0 - 97.0% of Salviae root Miltorrhizae, 1.0-19.0% Panax Notoginseng and 0.1-1.0 Borneol； (b) extract the ground root of Salviae Miltorrhizae and Panax Notoginseng obtained in step (a) in a hot aqueous reflux up to about 60-100 ° C in one or more extraction stage； (c) filter the extract obtained in step (b) and combine the extracts in the case of more than one extraction stage (b) to form a combined extract； (d) concentrate the extract from step (c) to an appropriate ratio between the volume of the concentrated extract and the weight of the herbal materials introduced to form a concentrated extract； (e) put ethanol in the concentrated extract of step (d) to a final concentration of approximately 50-85% ethanol, precipitate with ethanol and form a precipitated resolution； (f) concentrate the supernatant liquid of the precipitated resolution of step (e) to form a plaster with a relative density of approximately 1.15-1.45； and (g) mixing the plaster of step (f) with an appropriate amount of Borneol, thus producing the composition of the herbal extract of Salviae Miltorrhizae, Panax Notoginseng and Borneol root.Un proceso para la preparación de una composición para el tratamiento de la angina de pecho estable crónica, caracterizado porque comprende las etapas de: (a) obtener un material de partida triturado como sigue: 80,0 - 97,0 % de raíz de Salviae Miltorrhizae, 1,0 - 19,0 % de Panax Notoginseng y 0,1 - 1,0 de Borneol； (b) extraer la raíz molida de Salviae Miltorrhizae y Panax Notoginseng obtenida en la etapa (a) en un reflujo acuoso caliente hasta aproximadamente 60 - 100 °C en una o más etapa de extracción； (c) filtrar el extracto obtenido en la etapa (b) y combinar los extractos en el caso de más de una etapa de extracción (b) para formar un extracto combinado； (
