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NEPRILYSIN INHIBITORS
专利权人:
LLC;THERAVANCE BIOPHARMA ANTIBIOTICS IP
发明人:
HUGHES ADAM,FLEURY MELISSA,MORAN EDMUND J,FENSTER ERIK,GENDRON ROLAND
申请号:
ZA201402636
公开号:
ZA201402636B
申请日:
2014.04.10
申请国别(地区):
ZA
年份:
2015
代理人:
摘要:
In one aspect, the invention relates to compounds having the formula: where R1-R6, a, b, and Z are as defined in the specification, or a pharmaceutically acceptable salt thereof. These compounds have neprilysin inhibition activity. In another aspect, the invention relates to pharmaceutical compositions comprising such compounds; methods of using such compounds; and processes and intermediates for preparing such compounds.
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