Melissa FLEURY;Roland GENDRON;Adam D. HUGHES;Erik FENSTER
发明人:
Adam D. HUGHES,Erik FENSTER,Melissa FLEURY,Roland GENDRON
申请号:
US13666538
公开号:
US20130109639A1
申请日:
2012.11.01
申请国别(地区):
US
年份:
2013
代理人:
摘要:
In one aspect, the invention relates to compounds having the formula:where R1-R6, a, b, and Z are as defined in the specification, or a pharmaceutically acceptable salt thereof. These compounds have neprilysin inhibition activity. In another aspect, the invention relates to pharmaceutical compositions comprising such compounds; methods of using such compounds; and processes and intermediates for preparing such compounds.