Melissa Fleury;Roland Gendron;Adam D. Hughes;Erik Fenster;Edmund J. Moran
发明人:
Adam D. Hughes,Erik Fenster,Melissa Fleury,Roland Gendron,Edmund J. Moran
申请号：
US14838842
公开号：
US20160074352A1
申请日:
2015.08.28
申请国别(地区):
US
年份:
2016
代理人:
摘要：
In one aspect, the invention relates to compounds having the formula:where R1-R6, a, b, and Z are as defined in the specification, or a pharmaceutically acceptable salt thereof. These compounds have neprilysin inhibition activity. In another aspect, the invention relates to pharmaceutical compositions comprising such compounds； methods of using such compounds； and processes and intermediates for preparing such compounds.
