Jang, Myung Hyun,Kim, Dae Jin,Hwang, Sang Youn,Kim, Hyun Uk,Jung, Sung Youb,Kwon, Se Chang
申请号：
AU2014221534
公开号：
AU2014221534B2
申请日:
2014.02.26
申请国别(地区):
AU
年份:
2018
代理人:
摘要：
The present invention relates to: an insulin conjugate, wherein a non-peptidic polymer and an immunoglobulin Fc region are site-selectively connected, by a covalent bond, to an amino acid residue of a region excluding the N terminal of insulin β chain, and thus the binding force to an insulin receptor is improved, thereby increasing activity； an extended release preparation containing the same； and a method for preparing the same. The insulin conjugate of the present invention can provide an insulin preparation with remarkably improved
