REINHARDT JOEL C.,REINHARDT Joel C.,MACDONALD LYNN,MACDONALD Lynn,TORRES RICHARD,TORRES Richard,MORRA MARC R.,MORRA Marc R.,MARTIN JOEL H.,MARTIN Joel H.
申请号：
SI200831344
公开号：
SI2187964T1
申请日:
2008.08.08
申请国别(地区):
SI
年份:
2015
代理人:
摘要：
A human antibody or antigen-binding fragment of an antibody which specifically binds human nerve growth factor (NGF) with K D of 5 pM or less and does not cross-react with neurotrophin-3 (NT-3). The antibodies are useful in treating pain, including inflammatory pain, post-operative incision pain, neuropathic pain, fracture pain, osteoporotic fracture pain, post-herpetic neuralgia, osteoarthritis, rheumatoid arthritis, cancer pain, pain resulting from bums, gout joint pain, as well as diseases, such as hepatocellular carcinoma, breast cancer, and liver cirrhosis.
