The invention provides a craniotomy knife with quick disassembling function.In particular, it is an innovative design that can quickly change the cutting tool to reduce the operation time.To create a unique design,By means of the quick release mechanism,Quickly change the drill bit when cutting to save time.To avoid the loss of a lot of time when replacing a tool in the broken condition,Moreover, the clamping method of the invention is the same as that of the traditional clamping tool.It is through the thread between the clamping claw and the sleeve to carry out the clamping action.Therefore, the tool with different diameter can be clamped.And there is no need to have a clamping groove on the tool to clamp.Therefore, any conventional tool can be used.Further, the utility and advancement of the invention are convenient in use.本發明係提供一種具快拆功能之開顱手術用刀具,尤其是一種能夠快速的更換刀具來減少手術時間之創新型態設計;藉此創新獨特設計,使本發明藉由該快拆機構,在斷刀時快速更換鑽頭以節省時間,避免因斷刀狀態下更換刀具時會耗費許多時間的缺失,再者本發明夾持刀具的方式與傳統夾刀具相同,是透夾爪與套筒間的螺紋來進行夾持的動作,故可以夾持不同直徑大小之刀具,且刀具上不需要有卡槽來夾持,故任何一般傳統刀具皆可使用,進而使本發明達到使用上的便利之實用進步性者。