The invention relates to compounds of formula (I) which are suitable for the production of medicaments for the prophylaxis and therapy of diseases, whereby the course thereof involves the increased activity of matrix-metalloproteinases. Diseases belonging thereto are degenerative joint diseases, for example, osteo-arthrosis, spondylosis, chondroporosis after articulation injury or a long duration of articulation immobilisation after meniscus or patella injury or torn ligaments, or a disease of the connective tissue, such as collagenosis, periodontal diseases, problems with healing wounds, or a chronic disease of the locomotor system, such as inflammatory, immunological or metabolic-related acute or chronic arthritis, arthropathy, myalgies or troubles of the bone metabolism or ulceration, atherosclerosis or stenosis or an inflammatory disease or cancer, a metastatic tumour, cachexia, anorexia or septic shock.
