The disclosure relates to conjugate based antifungal and antibacterial prodrugs. In an embodiment the prodrugs are of formula (i) (AFA)m-X-(L)n, wherein: AFA is an antifungal agent ； L is a carrier； X is a linker； m ranges from 1 to 10； and n ranges from 2 to 10； (ii) [(AFA)m’-X]p-L, wherein: AFA is an antifungal agent ； L is a carrier； X is a linker； m’ is 1 to 10； and p is 1, 3, 4 or 5； or (iii) AFA-[X-(L)n’]q, wherein: AFA is an antifungal agent ； L is a carrier； X is a linker； n’ is 1 to 10； and q is 1 to 10, provided that q and n’ are not both 1. Examples of the prodrugs include ketoconazole methylene palmitate, ketoconazole-propylene glycol-hexapeptide, clindamycin-glycolic acid-PLGA and clindamycin linoleate. The prodrugs may be useful in the treatment of dandruff or acne.
