PROBLEM TO BE SOLVED: To provide a compound useful as an NK receptor antagonist.SOLUTION: There are provided a compound expressed by formula (I) (wherein, A shows a benzene ring which may have a substituent, R shows a hydrocarbon group or the like, which may have a hydrogen atom and a substituent, X1 and X2 show a bond or the like, X3 shows a methylene group that has a substituent, Y shows a bond or the like, and Z shows a hydrocarbon group or the like. which may have a substituent), and its salt.COPYRIGHT: (C)2013,JPO&INPIT【課題】NK受容体拮抗薬として有用な化合物を提供する。【解決手段】式(I)【化1】[式中、Aは置換基を有していてもよいベンゼン環を示し、Rは水素原子、置換基を有していてもよい炭化水素基等を示し、X1およびX2はそれぞれ結合手等を示し、X3は置換基を有するメチレン基を示し、Yは結合手等を示し、Zは置換基を有していてもよい炭化水素基等を示す。]で表される化合物またはその塩。
