Angiogensis models using nestin-expressing stem cells to image nascent blood vessels

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专利权人:

ANTICANCER, INC.

发明人:

AMOH YASUYUKI,LI LINGNA,YANG MENG,JIANG PING

申请号：

US20040977219

公开号：

US2005170330(A1)

申请日:

2004.10.28

申请国别(地区):

美国

年份:

2005

代理人:

摘要：

The disclosed invention relates to the observation that nestin expression is a marker for endothelial cell proliferation. Nestin expression is particularly useful as a marker for angiogenesis, particularly for tumor-related angiogenesis. Specifically, nestin serves as an excellent endothelium marker for brain tumors such as gliomas, hemangioblastomas, Schwannomas, medulloblastomas, and meningiomas. Accordingly, the disclosed invention relates to the use of this marker as a basis to model angiogenic activity.

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