HAILES, HELEN CLAIRE,TABOR, ALETHEA BERNICE,MOHD MUSTAPA, MOHD FIROUZ,HART, STEPHEN LEWIS,TAGALAKIS, ARISTIDES
申请号：
CA3016614
公开号：
CA3016614A1
申请日:
2017.03.10
申请国别(地区):
CA
年份:
2017
代理人:
摘要：
A lipid comprising a tri-chain cation of formula (la) having a cationic head group and three C12-24 hydrocarbyl groups for use in non-viral gene delivery systems, for example in the formation of lipopolyplex transfection vectors. Exceptionally good nucleic acid transfection is observed when nucleic acid and targeting peptides are formulated with the lipid of the invention (or lipid formulated with a co-lipid) into a LPD complex.
