Michael Mitchell,Amanda Chung,Pedro P. G. Guimaraes,Omar F. Khan,Robert S. Langer,Daniel Griffith Anderson
申请号：
US16002965
公开号：
US20180353435A1
申请日:
2018.06.07
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The present invention provides compositions (e.g., nanoparticles) comprising a conjugated polyethyleneimine (PEI) polymer (a “conjugated lipomer”), or a pharmaceutically acceptable salt thereof, and a lipid-PEG conjugate, wherein the conjugated lipomer of Formula (I) contains one or more groups of the formula (iii). Compositions of the invention are useful for the delivery of active agents, for example, for the treatment of disease.
