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INDUCTION OF TUMOR IMMUNITY BY VARIANTS OF FOLATE BINDING PROTEIN
专利权人:
发明人:
Constantin G. IOANNIDES,George E. PEOPLES
申请号:
US14339797
公开号:
US20150175658A1
申请日:
2014.07.24
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The present invention is directed to variants of antigens comprising folate binding protein epitopes as a composition associated with providing immunity against a tumor in an individual. The variant is effective in inducing cytotoxic T-lymphocytes but preferably not to the extent that they become sensitive to silencing by elimination, such as by apoptosis, or by anergy, as in unresponsiveness.
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