THE HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE; INC.
发明人:
GEORGE E. PEOPLES,CONSTANTIN G. IOANNIDES
申请号:
PT11004714
公开号:
PT2371854E
申请日:
2002.03.08
申请国别(地区):
PT
年份:
2014
代理人:
摘要:
The present invention is directed to variants of antigens comprising folate binding protein epitope (E39) as a composition associated with providing immunity against a tumor in an individual. The variant is effective in inducing cytotoxic T-lymphocytes but preferably not to the extent that they become sensitive to silencing by elimination, such as by apoptosis, or by anergy, as in unresponsiveness.