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Induction of tumor immunity by variants of folate binding protein
专利权人:
BOARD OF REGENTS; THE UNIVERSITY OF TEXAS SYSTEM OFFICE OF THE GENERAL COUNSEL
发明人:
IOANNIDES CONSTANTIN G.,Ioannides Constantin G.,PEOPLES GEORGE E.,Peoples George E.
申请号:
SI200231046
公开号:
SI2371854T1
申请日:
2002.03.08
申请国别(地区):
SI
年份:
2014
代理人:
摘要:
The present invention is directed to variants of antigens comprising folate binding protein epitope (E39) as a composition associated with providing immunity against a tumor in an individual. The variant is effective in inducing cytotoxic T-lymphocytes but preferably not to the extent that they become sensitive to silencing by elimination, such as by apoptosis, or by anergy, as in unresponsiveness.
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