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תרכובות טטרה–הידרוקרבוזול וקרבוזול קרבוקסמיד שימושיות כמעכבי קינאז
专利权人:
BRISTOL-MYERS SQUIBB COMPANY
发明人:
申请号:
IL24329615
公开号:
IL243296A
申请日:
2015.12.22
申请国别(地区):
IL
年份:
2018
代理人:
摘要:
R1 is F, Cl, —CN, or —CH3; R2 is Cl or —CH3; R3 is —C(CH3)2OH or —CH2CH2OH; Ra is H or —CH3; each Rb is independently F, Cl, —CH3, and/or —OCH3; and n is zero, 1, or 2. Also disclosed are methods of using such compounds as inhibitors of Bruton's tyrosine kinase (Btk), and pharmaceutical compositions comprising such compounds. These compounds are useful in treating, preventing, or slowing the progression of diseases or disorders in a variety of therapeutic areas, such as autoimmune diseases and vascular disease.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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