ID Pharma Co., Ltd.;Japan as represented by the Director-General of National Institute of Infectious Diseases
发明人:
Tetsuro MATANO,Makoto INOUE,Hiroto HARA,Tsugumine SHU
申请号：
US16342070
公开号：
US20200155669A1
申请日:
2017.11.17
申请国别(地区):
US
年份:
2020
代理人:
摘要：
In this invention, a non-infectious particle has been produced, comprising a pathogen antigen protein caused to be expressed on the surface of a virus particle having at least one species of paramyxovirus envelope protein missing from the particle. This particle has been found to hold within the particle a large amount of antigen protein compared to an infectious particle, and to be capable of eliciting a host immune response with extremely high efficiency. The non-infectious particle according to the present invention is useful as a vaccine against a pathogenic virus, or the like.
