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VACCIN CONTRE DES MALADIES INFECTIEUSES UTILISANT DES PARTICULES DE PARAMYXOVIRUS NON INFECTIEUSES
专利权人:
ID Pharma Co., Ltd.;Japan as Represented by The Director-General of National Institute of Infectious Diseases
发明人:
申请号:
EP17871536.3
公开号:
EP3542818A1
申请日:
2017.11.17
申请国别(地区):
EP
年份:
2019
代理人:
摘要:
In this invention, a non-infectious particle has been produced, comprising a pathogen antigen protein caused to be expressed on the surface of a virus particle having at least one species of paramyxovirus envelope protein missing from the particle. This particle has been found to hold within the particle a large amount of antigen protein compared to an infectious particle, and to be capable of eliciting a host immune response with extremely high efficiency. The non-infectious particle according to the present invention is useful as a vaccine against a pathogenic virus, or the like.
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