A carrier device and methods of use are described. The device and methods aredirected toward implanting in biologicaltissue and optionally for propelling in a biological tissue and for releasinga medical payload in a biological tissue according to remotetrigger. The carrier device includes at least one element sensitive to theexternal stimuli. When external stimuli are sent through thetissue, the responsive element provides release of the functional material. Insome embodiments, payload release can be started, stopped,and restarted at a later time or place. Individual carrier devices can beselectively triggered by implementing different elements in thedevices, each element is sensitive to different stimuli. In addition topayload release, devices of this invention are equipped with apropelling element, the propelling element is responsive to external stimulithat enables propulsion and navigation of the device.
